{"id":126,"date":"2021-06-21T16:45:54","date_gmt":"2021-06-21T08:45:54","guid":{"rendered":"http:\/\/nnwilking.gotoip3.com\/?p=126"},"modified":"2022-02-18T15:14:15","modified_gmt":"2022-02-18T07:14:15","slug":"%e6%b5%81%e5%bc%8f%e7%bb%86%e8%83%9e%e6%9c%af%e6%a3%80%e6%b5%8b","status":"publish","type":"post","link":"http:\/\/nnwilking.com\/bio_tech\/126\/","title":{"rendered":"\u6d41\u5f0f\u7ec6\u80de\u672f\u68c0\u6d4b"},"content":{"rendered":"\n
\u7531\u4e8e\u6d41\u5f0f\u7ec6\u80de\u4eea\u80fd\u591f\u5206\u6790\u6837\u672c\u4e2d\u4e0d\u540c\u7ec6\u80de\u7c7b\u578b\u7684\u591a\u4e2a\u53c2\u6570\uff0c\u56e0\u6b64\u5b83\u53ef\u4ee5\u4ece\u5c11\u91cf\u8840\u6db2\u4e2d\u83b7\u53d6\u975e\u5e38\u4e30\u5bcc\u4e14\u5177\u6709\u4e34\u5e8a\u4ef7\u503c\u7684\u6570\u636e\u3002<\/p>\n\n\n\n
\u7136\u800c\uff0c\u6d41\u5f0f\u7ec6\u80de\u4eea\uff0c\u4e0d\u5bb9\u6613\u719f\u7ec3\u638c\u63e1\uff0c\u9700\u8981\u5728\u8bbe\u5907\u548c\u6280\u672f\u57f9\u8bad\u65b9\u9762\u8fdb\u884c\u5927\u91cf\u6295\u8d44\u3002<\/p>\n\n\n\n
\u56e0\u6b64\uff0c\u5bf9\u4e8e\u8bb8\u591a\u7814\u7a76\u4eba\u5458\u800c\u8a00\uff0c\u5c06\u6d41\u5f0f\u7ec6\u80de\u4eea\u5916\u5305\u7ed9\u5408\u540c\u7814\u7a76\u7ec4\u7ec7 (CRO) \u65e2\u5177\u6709\u6210\u672c\u6548\u76ca\uff0c\u53c8\u662f\u786e\u4fdd\u4ece\u4ed6\u4eec\u7684\u6837\u672c\u4e2d\u83b7\u5f97\u6700\u9ad8\u8d28\u91cf\u6570\u636e\u7684\u6700\u4f73\u65b9\u5f0f\u3002<\/p>\n\n\n\n
\u670d\u52a1\u9879\u76ee<\/strong><\/p>\n\n\n\n a) \u514d\u75ab\u8868\u578b Immunophenotyping\uff1b<\/p>\n\n\n\n b) \u7ec6\u80de\u5206\u578b Cell Sorting\uff1b<\/p>\n\n\n\n c) \u53d7\u4f53\u5360\u7528 Receptor Occupancy\uff1b<\/p>\n\n\n\n d) \u7ec6\u80de\u529f\u80fd\u68c0\u6d4b\uff08\u51cb\u4ea1\u3001\u5468\u671f\u3001ROS\u3001\u7ebf\u7c92\u4f53\u819c\u7535\u4f4d\uff09Functional Cellular Assays\uff1b<\/p>\n\n\n\n e) \u7ec6\u80de\u5185\u7ec6\u80de\u56e0\u5b50\u67d3\u8272Intracellular Cytokine staining\uff1b<\/p>\n\n\n\n f)T\u7ec6\u80de\u6d3b\u5316\/\u8017\u7aed\u68c0\u6d4b T Cell Activation\/Exhaustion Assays<\/p>\n\n\n\n